Figure 10.

Deletion of PKCα does not change the scotopic ERG c-wave. (A) Low-pass filtered scotopic ERGs from WT (n = 62, black) and PKC-KO (n = 52, red) eyes were averaged and plotted over a time course of 5 seconds. For (A–D) the numbers to the right of the traces represent stimulus strength in log(cd-s/m²). (B) Low-pass filtered scotopic ERGs of a WT mouse following intravitreal injection of one eye with APB (red) to block the RBC light response and the other eye with PBS (black). (C) Low-pass filtered scotopic ERGs of a PKC-KO mouse mouse following intravitreal injection of one eye with APB (red) to block the RBC light response and the other eye with PBS (black). (D) Scotopic ERG c-waves from TRPM1-KO (n = 3, black) and PKC-TRPM1 double-KO (n = 8, red) eyes were averaged and plotted versus postflash time.