Table 2.
| |||||
---|---|---|---|---|---|
Entry | Allene-yne | X | R | Conditions | Yield 10 (%) |
1 | 8b | C(CO2Et)2 | H | a | 92 |
2 | 8b | b | 50 | ||
3 | 8c | Me | a | 87 | |
4 | 8c | b | 27 | ||
5 | 8d | H | a | 78 | |
6 | 8e | C(CH2OH)2 | Me | a | 59 |
7 | 8f | NTs | Me | a | 92 |
8 | 8g | H | a | 73 | |
9 | 8h | O | Me | a | 49 |
10 | 8i | H | a | 44 |
Syringe pump addition of allene-yne to Rh(I) solution was utilized.
Allene-yne was added to the solution all at once.