Table 3.

Clinico-pathological factors associated with DNMT1 overexpression in astrocytic tumour patients from multiple logistic regression

Variable	Crude ORa (CI 95%)	Adjusted ORb (CI 95%)	Wald statisticb (df)	p-valueb
WHO grade
I	1	1
II	2.933 (0.657, 13.093)	2.944 (0.659, 13.163)	1.998 (1)	0.158
III	5.867 (1.075, 32.002)	5.802 (1.059, 31.785)	4.105 (1)	0.043
IV	41.600 (4.219, 410.222)	40.663 (4.069, 406.347)	9.953 (1)	0.002
MGMT percentage	0.985 (0.956, 1.015)	0.997 (0.963, 1.032)	0.420 (1)	0.863

OR: odd ratio, df: degree of freedom, CI: confident interval, RE: reduced expression, OE: overexpression;

^asimple logistic regression;

^bmultiple logistic regression.