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Effect of microRNA-127 silenced on cell cycle and apoptosis in U251/Adr and U87-MG/Adr. A. The effects of microRNA-127 silence on cell cycle. Down-regulating microRNA-127 expression led to the percentage of cells in G1/G0 phase increased obviously (P<0.05) and the microRNA-127 silencing increased the sensitivity to ADR. B. microRNA-127 silencing induced cell apoptosis in U251/Adr and U87-MG/Adr cell lines (*P<0.05, **P<0.01).
