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. 2015 Jun 1;8(6):6434–6441.

Figure 4.

Figure 4

Formononetin treatment decreased the expression of HDAC5. U87MG cells was treated with doxorubicin or in combination with formononetin (100 μM) for 48 h. Western blot was performed to determine the expression of HDAC5 in glioma cells incubated with doxorubicin (A and B) or in combination with formononetin (100 μM) (C and D). U87MG cells were transfected with the plasmid encoding HDAC5 (E) and cell viability was determined by CCK-8 methods after incubation with doxorubicin alone or combined with formononetin (F). *P < 0.05; **P < 0.01.