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MTT assay showed that proliferation was reduced by siRNA-mediated reduction of Dsc3 or EGFR and by PI3K/Akt pathway inhibitor treatment, both with or without FSH treatment. These results suggest that the Dsc3/EGFR/Akt axis functions in mediating ovarian cell proliferation, which is enhanced by FSH. A. Hey cells; B. HO8910 cells.
