Figure 1.

Histological examination of neuronal damage and TUNEL-positive cells. A. Survival analysis showed that heatstroke rats had a poor prognosis compared to heatstroke rats with AG490 treatment. B. After 1 h heat exposure, the AG490 treatment protected the damage of edema and disappearance of nucleus in heatstroke-induced rats. C. AG490 treatment suppressed the increase of the number of TUNEL-positive cells of hippocampal nucleus in heatstroke-induced rats. #P < 0.01 compared the control group. *P < 0.01 compared with the heatstroke group.