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Effect of AG490 on JAK2/STAT3 pathway and inflammation. AG490 treatment suppressed activation of JAK2/STAT3 pathway and increase of inflammation related protein, MMP2 and MMP-9. And AG490 treatment also inhibition of inflammation factors secretions induced by heatstroke. #P < 0.01 compared with the control group. *P < 0.01 compared with the heatstroke group.
