Table 3.
microRNAs and pathways related to drug resistance in ovarian cancer
| Pathway | Numbers of microRNAs | P value | Associations with drug resistance in ovarian cancer (Ref.) | |
|---|---|---|---|---|
| microRNA199a-5p | Focal adhesion | 8 | 2.58E-13 | YES [21] |
| microRNA199a-3p | PI3K-Akt Signaling pathway | 7 | 2.24E-12 | YES [22] |
| microRNA199b-3p | Ubiquitin mediated proteolysis | 7 | 4.76E-12 | YES [23] |
| microRNA215 | ErbB signaling pathway | 9 | 1.78E-09 | YES [24] |
| microRNA363 | Regulation of actin cytoskeleton | 8 | 2.74E-09 | - |
| microRNA335 | Long-term potentiation | 6 | 2.74E-09 | - |
| microRNA18b | Gap junction | 8 | 2.74E-09 | YES [25] |
| microRNA141 | Ascorbate and aldarate metabolism | 3 | 9.60E-09 | - |
| microRNA-645 | Calcium signaling pathway | 8 | 9.60E-09 | YES [26] |
| MAPK signaling pathway | 9 | 4.30E-07 | YES [27] |
-indicates no reports or an inability to retrieve relevant reports.