Table 2.
Quantification of cells SIRT1, Bcl-2, Bax and apoptosis in CA1 region each group (400-fold visual field)
Group | SIRT1 | Bcl-2 | Bax | Apoptosis |
---|---|---|---|---|
Sham | 34.68±2.86 | 55.38±5.65 | 44.36±2.03 | 13.01±1.30 |
D-gal | 36.20±3.37 | 67.35±5.32a | 59.56±3.83a | 50.06±5.67a |
EPO | 66.22±5.54b,c | 84.78±5.48b,c | 48.48±2.73b | 25.38±3.02b,c |
VitE | 50.80±6.20b | 74.18±7.48b | 49.54±2.23b | 38.27±3.56b |
Data are expressed as mean ± SD; 10 rats in each group.
P < 0.05, vs. Sham group;
P < 0.05, vs. D-gal group;
P < 0.05, vs. VitE group; (analysis of variance).