Table 1.
Correlation of PNI with clinicopathological features in locally advanced ESCC patients
| N | PNI-positive | PNI-negative | P | |
|---|---|---|---|---|
| Age | 0.280 | |||
| < 60 | 117 | 22 (18.8%) | 95 (81.2%) | |
| ≥ 60 | 126 | 32 (25.4%) | 94 (74.6%) | |
| Sex | 0.702 | |||
| Male | 194 | 42 (21.6%) | 152 (78.4%) | |
| Female | 49 | 12 (24.5%) | 37 (75.5%) | |
| Location | 0.475 | |||
| Proximal esophagus | 18 | 2 (11.1%) | 16 (88.9%) | |
| Mid esophagus | 165 | 39 (23.6%) | 126 (76.4%) | |
| Distal esophagus | 60 | 13 (21.7%) | 47 (78.3%) | |
| Differentiation | 0.365 | |||
| Well | 4 | 0 (0%) | 4 (100%) | |
| Moderately | 106 | 21 (19.8%) | 85 (80.2%) | |
| Poorly | 133 | 33 (24.8%) | 100 (74.2%) | |
| Blood vessel invasion | 0.758 | |||
| Absent | 127 | 27 (21.3%) | 100 (78.7%) | |
| Present | 116 | 27 (23.3%) | 89 (76.7%) | |
| T stage | 0.043 | |||
| pT1-2 | 51 | 3 (9.6%) | 48 (90.4%) | |
| pT3-4 | 192 | 51 (26.5%) | 141 (73.5%) | |
| N stage | 0.442 | |||
| pN0 | 106 | 21 (19.8%) | 85 (81.2%) | |
| pN+ | 137 | 33 (24.1%) | 104 (78.4%) | |
| AJCC stage | 0.02 | |||
| II | 125 | 20 (16%) | 105 (84%) | |
| III | 118 | 34 (28.8%) | 84 (71.2%) | |
| First failure location | ||||
| Local recurrence | 0.021 | |||
| Absent | 124 | 20 (16.1%) | 104 (83.9%) | |
| Present | 119 | 34 (28.5%) | 85 (71.5%) | |
| Distant metastasis | 0.029 | |||
| Absent | 170 | 31 (18.2%) | 139 (81.8%) | |
| Present | 73 | 23 (31.5%) | 50 (68.5%) |