Table 4.
Association of miR-21 expression level with clinical parameters
| cases | Expression Level of miR-21 | P-value | ||
|---|---|---|---|---|
|
| ||||
| High (n, %) | Low (n, %) | |||
| Age (years) | ||||
| < 45 | 18 | 10 (55.56) | 8 (44.44) | NS |
| ≥ 45 | 12 | 6 (50.00) | 6 (50.00) | |
| Tumor size | ||||
| < 4.0 cm | 22 | 12 (54.54) | 10 (45.46) | NS |
| ≥ 4.0 cm | 8 | 4 (50.0) | 4 (50.0) | |
| Histology Type | ||||
| G1 | 18 | 8 (44.4) | 10 (55.6) | 0.065 |
| G2 | 9 | 6 (66.7) | 3 (33.3) | |
| G3 | 3 | 2 (66.7) | 1 (33.3) | |
| FIGO stage | ||||
| Ib1 | 6 | 3 (50.0) | 3 (50.0) | 0.124 |
| Ib2 | 17 | 12 (70.6) | 5 (29.4) | |
| IIa | 7 | 5 (71.4) | 2(28.6) | |
| Lymph node metastasis | ||||
| Absent | 25 | 7 (28.0) | 18 (72.0) | 0.015 |
| Present | 5 | 4 (80.0) | 1 (20.0) | |
| Vascular invasion | ||||
| Absent | 22 | 6 (27.3) | 16 (72.7) | 0.023 |
| Present | 8 | 6 (75.0) | 2 (25.0) | |
| Depth of invasion | ||||
| < 1/2 layer | 22 | 6 (27.3) | 16 (72.7) | 0.031 |
| ≥ 1/2 layer | 8 | 6 (75.0) | 2 (25.0) | |