Table 1.
Correlation between the presence of squamous differentiation and clinicopathological features in patients with upper urinary tract urothelial carcinoma who underwent nephroureterectomy
| Squamous differentiation | ||||
|---|---|---|---|---|
|
|
||||
| Clinical or pathological features | Total N | Absent | Present | P value |
| All cases | 140 | 117 (84%) | 23 (16%) | |
| Sex | 0.083 | |||
| Male | 101 | 81 (80%) | 20 (20%) | |
| Female | 39 | 36 (92%) | 3 (8%) | |
| Age | 0.26 | |||
| < 70 | 76 | 66 (87%) | 10 (13%) | |
| ≥ 70 | 64 | 51 (80%) | 13 (20%) | |
| Side | 0.36 | |||
| Left | 73 | 63 (86%) | 10 (14%) | |
| Right | 67 | 54 (81%) | 13 (19%) | |
| Tumor location | 0.77 | |||
| Renal pelvis | 89 | 75 (84%) | 14 (16%) | |
| Ureter | 51 | 42 (82%) | 9 (18%) | |
| Tumor architecture | 0.63 | |||
| Papillary | 103 | 87 (84%) | 16 (16%) | |
| Sessile | 37 | 30 (81%) | 7 (19%) | |
| Grade | 0.014 | |||
| Grade 1 or 2 | 63 | 58 (92%) | 5 (8%) | |
| Grade 3 | 77 | 59 (77%) | 18 (23%) | |
| Lymphovascular invasion | 0.022 | |||
| Absent | 79 | 71 (90%) | 8 (10%) | |
| Present | 61 | 46 (75%) | 15 (25%) | |
| Concomitant carcinoma in situ | 0.04 | |||
| Absent | 76 | 68 (89%) | 8 (11%) | |
| Present | 64 | 49 (77%) | 15 (23%) | |
| Tumor stage | 0.0211 | |||
| pTa or pTis | 36 | 34 (94%) | 2 (6%) | |
| pT1 | 25 | 22 (88%) | 3 (12%) | |
| pT2 | 11 | 9 (82%) | 2 (18%) | |
| pT3 | 60 | 46 (77%) | 14 (23%) | |
| pT4 | 8 | 6 (75%) | 2 (25%) | |
| Lymph node metastasis | 0.0006 | |||
| Absent | 122 | 107 (88%) | 15 (12%) | |
| Present | 18 | 10 (56%) | 8 (44%) | |
| Adjuvant chemotherapy | 0.041 | |||
| No | 98 | 86 (88%) | 12 (12%) | |
| Yes | 42 | 31 (74%) | 11 (26%) | |
1
pTa-pT1 vs. pT2-pT4.