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. 2015 Jun 1;8(6):7210–7216.

Table 2.

Expression of apoptotic genes

Time course (hours) Condition Genes

CYCS Casp3 Casp8 Casp9
0 Normoxia 1.00 (0.58~1.73) 1.00 (0.83~1.20) 1.00 (0.83~1.22) 1.00 (0.82~1.22)
Hypoxia 0.22 (0.17~0.27) 0.15 (0.12~0.17) 0.33 (0.27~0.40) 0.03 (0.03~0.04)*
8 Normoxia 0.36 (0.31~0.42) 0.29 (0.25~0.34) 0.35 (0.28~0.44) 0.22 (0.19~0.26)
Hypoxia 0.20 (0.17~0.23) 0.46 (0.39~0.54) 0.21 (0.18~0.24) 0.03 (0.03~0.04)
24 Normoxia 0.38 (0.31~0.46) 1.12 (0.95~1.31) 0.32 (0.27~0.37) 0.62 (0.53~0.74)
Hypoxia 0.41 (0.36~0.47) 6.15 (4.08~9.26)* 4.43 (3.92~5.00)* 0.63 (0.52~0.76)
72 Normoxia 0.25 (0.18~0.36) 0.29 (0.25~0.34) 0.31 (0.26~0.38) 0.10 (0.08~0.13)
Hypoxia 1.02 (0.86~1.21) 2.47 (2.14~2.85)* 3.10 (2.52~3.81)* 1.42 (1.16~1.75)*

The genes expression levels were calcaulted by the 2-ΔΔCT method. Data were presented as 2-ΔΔCT and range.

*

Indicated significance (p < 0.05) when compared with normoxia or hypoxia.

CYCS, Cytochrome C, Somatic; Casp, caspase.