Table 3.
Association between NCOA2 polymorphisms and BMI or serum indices
| rs41391448 | F | P * | rs10504473 | F | P * | |||||
|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
|||||||||
| AA (n = 368) | AG (n = 109) | GG (n = 12) | AA (n = 134) | AC (n = 243) | CC (n = 128) | |||||
| BMI (kg/m2) | 24.37 ± 3.18 | 24.09 ± 3.25 | 24.08 ± 3.64 | 0.35 | 0.71 | 24.13 ± 3.14 | 24.35 ± 3.02 | 24.26 ± 3.56 | 0.31 | 0.73 |
| TG (mmol/l) | 1.69 ± 1.57 | 1.51 ± 1.30 | 1.63 ± 2.01 | 0.07 | 0.93 | 1.77 ± 1.50 | 1.68 ± 1.63 | 1.53 ± 1.17 | 1.51 | 0.22 |
| TC (mmol/l) | 5.20 ± 1.13 | 5.21 ± 1.08 | 5.05 ± 1.36 | 0.18 | 0.83 | 5.18 ± 0.93 | 5.26 ± 1.24 | 5.11 ± 1.08 | 0.71 | 0.49 |
| HDL-C (mmol/l) | 1.24 ± 0.51 | 1.23 ± 0.45 | 1.13 ± 0.69 | 0.22 | 0.81 | 1.30 ± 0.55 | 1.21 ± 0.49 | 1.22 ± 0.50 | 0.77 | 0.47 |
| LDL-C (mmol/l) | 3.14 ± 1.03 | 3.21 ± 0.92 | 2.72 ± 1.17 | 1.37 | 0.25 | 1.34 ± 0.47 | 1.28 ± 0.40 | 1.29 ± 0.40 | 0.09 | 0.91 |
BMI, TC, LDL-C were presented as mean ± standard deviation; TG and HDL-C were presented as median ± interquartile range; Bold values are statistically significant (P < 0.05);
*
P value was calculated with analysis of covariance adjusted for age and sex.