Table 2.
Grades of disc degeneration among LDD patients with different TRAIL genotypes and alleles
| Genotypes and alleles | n | Grade 2 | Grade 3 | Grade 4 | P value |
|---|---|---|---|---|---|
| 1525 GG/1595 CC | 46 | 14 (30.43) | 12 (26.09) | 20 (43.48) | |
| 1525 GA/1595 CT | 71 | 22 (30.99) | 18 (25.35) | 31 (43.66) | |
| 1525 AA/1595 TT | 36 | 20 (55.56) | 9 (25.00) | 7 (19.44) | 0.012 |
| 1525 G/1595 C | 163 | 50 (30.67) | 42 (25.77) | 71 (43.59) | |
| 1525 A/1595 T | 143 | 62 (43.36) | 36 (25.17) | 45 (31.47) | 0.012 |
TRAIL, tumor necrosis factor related apoptosis-inducing ligand; LDD, lumbar disc degeneration.