Table 2.
Genotypes and alleles distribution of -31G/C, -625G/C, 9194A/G and 9809T/C
| Genotype/allelotype | Cases n=104 (%) | Controls n=104 (%) | χ2 | P value | OR (95% CI) |
|---|---|---|---|---|---|
| -31G/C | |||||
| GG | 20 (19.2) | 30 (28.8) | - | - | 1.00 |
| GC | 49 (47.1) | 51 (49.0) | 1.087 | 0.297 | 1.44 (0.72-2.87) |
| CC | 35 (33.6) | 23 (22.1) | 4.447 | 0.035 | 2.28 (1.05-4.94) |
| G | 89 (42.8) | 111 (53.4) | - | - | 1.00 |
| C | 119 (57.2) | 97 (46.6) | 4.661 | 0.031 | 1.53 (1.04-2.25) |
| -625G/C | |||||
| GG | 54 (51.9) | 57 (54.8) | - | - | 1.00 |
| GC | 39 (37.5) | 39 (37.5) | 0.033 | 0.855 | 1.06 (0.59-1.88) |
| CC | 11 (10.6) | 8 (7.7) | 0.555 | 0.456 | 1.45 (0.54-3.88) |
| G | 147 (70.7) | 153 (73.6) | - | - | 1.00 |
| C | 61 (29.3) | 55 (26.4) | 0.430 | 0.512 | 1.15 (0.75-1.77) |
| 9194A/G | |||||
| AA | 44 (42.3) | 56 (53.8) | - | - | 1.00 |
| AG | 42 (40.4) | 40 (38.5) | 0.942 | 0.332 | 1.34 (0.74-2.40) |
| GG | 18 (17.3) | 8 (7.7) | 5.256 | 0.022 | 2.86 (1.14-7.20) |
| A | 130 (62.5) | 152 (73.1) | - | - | 1.00 |
| G | 78 (37.5) | 56 (26.9) | 5.328 | 0.021 | 1.63 (1.08-2.47) |
| 9809T/C | |||||
| CC | 32 (30.8) | 33 (31.7) | - | - | 1.00 |
| CT | 52 (50.0) | 54 (51.9) | 0.000 | 0.982 | 0.99 (0.54-1.84) |
| TT | 20 (19.2) | 17 (16.3) | 0.219 | 0.639 | 1.21 (0.54-2.72) |
| C | 116 (55.8) | 120 (57.7) | - | - | 1.00 |
| T | 92 (44.2) | 82 (39.4) | 0.555 | 0.456 | 1.16 (0.78-1.72) |