Table 4.
The association of MDM2 rs937283 and rs769412 polymorphisms with alcohol drinking with larynx carcinoma risk
| SNPs | Variates | Cases | Controls | P | OR (95% CI) |
|---|---|---|---|---|---|
| rs937283 | |||||
| + | + | 30 | 48 | 1.00 | |
| + | - | 35 | 32 | 1.31 | 1.75 (0.90-3.39) |
| - | + | 11 | 10 | 0.32 | 1.76 (0.67-4.64) |
| - | - | 50 | 30 | 0.00 | 2.67 (1.40-5.07) |
| rs769412 | |||||
| + | + | 35 | 47 | 1.00 | |
| + | - | 57 | 52 | 0.24 | 1.47 (0.83-2.62) |
| - | + | 6 | 11 | 0.79 | 0.73 (0.25-2.17) |
| - | - | 28 | 10 | 0.00 | 3.76 (1.62-8.75) |
Note: “+” and “-” represents wild and mutant genotypes in SNP column, respectively. In variate column, “+” and “-” represents no drinking and alcohol drinking, respectively.