Table 6.
The titers of HAV (YN5) adapted in human diploid cells
| Virus Passage NO. | Infectivity titer in Walvax-2 cells(log CCID50/ml)a | Infectivity titer in MRC-5 cells(log CCID50/ml) a | Pb |
|---|---|---|---|
| 23(original) | 7.0 | 7.0 | |
| 24 | 7.32± 0.28 | 6.27± 0.27 | <0.05 |
| 25 | 7.47± 0.09 | 7.01± 0.23 | >0.05 |
| 26 | 7.50±0.17 | 7.35± 0.14 | >0.05 |
| 27 | 7.62± 0.06 | 7.18± 0.38 | >0.05 |
| 28 | 7.97± 0.09 | 7.50± 0.23 | >0.05 |
| 29 | 8.21± 0.29 | 7.54± 0.24 | <0.05 |
| 30 | 7.81± 0.17 | 7.35± 0.14 | <0.05 |
| 31 | 7.65± 0.14 | 7.36± 0.34 | >0.05 |
a±SD.
b Significance of difference (P value) determined by 2-tailed t-test