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Endoplasmic reticular stress is involved in the activation of autophagy of INS-1 cells induced by LRG. INS-1 cells were treated with normal saline (CON), FFA, LRG and FFA + LRG for 24 h. (A) CHOP and GRP78 proteins were detected using immunoblotting, the results were normalized to that of GAPDH. Quantification of the expression levels of (B) CHOP and (C) GRP78. LRG, liraglutide; CON, control; FFA, free fatty acids.
