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Mechanism of function of NPRL2 on protein expression. Protein expression levels of p-AKT and the caspase-3, Bcl2 and Bax apoptosis-associated genes were determined using western blotting. Control, cells without transfection; mock, cells transfected with mock vector; NPRL2, cells transfected with NPRL2-overexpression vector. NPRL2, nitrogen permease regulator-like-2; p-, phosphorlyated; Bcl2, B-cell lymphoma 2; Bax, Bcl-2-associated X protein.
