Table II.

Top four enriched Kyoto Encyclopedia of Genes and Genomes pathway categories of upregulated genes.

Pathway	P-value	Upregulated genes
Cytokine-cytokine receptor interaction	6.77×10−8	TGFB1, CXCR4, TNFRSF1B, CD70, CCL5, EGFA, VEGFB, TNFRSF10B, TNF, IL10RA, IL3RA, TNFSF9, CSF2RA, EPOR, TNFSF13B, FLT3LG, CD40, IL2RG, IL23A, CSF1, CXCL16, PDGFA, TNFRSF12A, CRLF2, CCL2, CCL24, CTF1, CCL3, FIGF, CCL13, INHBE, LTA, CCL4, CCL21, XCR1, LEP, TNFSF18, CCL3L3, CL3L1, GDF6, CCL4L2, IL17B, GH1, CXCL11, TNFRSF4, INHBA, CCR7, CCR5, CCL26, IFNB1, GDF5, TNFRSF18, CCL8
Osteoclast differentiation	1.07×10−4	SPI1, CYBA, TGFB1, NCF4, JUND, RAC1, STAT1, GAB2, NFKBIA, FCGR1A, JUN, PPARG, IKBKG, LILRB5, TNF, NFKB2, LILRA5, RELB, LILRB2, OSCAR, NCF1, SOCS3, CSF1, SOCS1, FCGR1B, BLNK, LILRB3, LILRA6, IFNB1
Steroid biosynthesis	1.13×10−4	FDFT1, SQLE, DHCR7, EBP, SDHL, TM7SF2, HSD17B7, CYP51A1, SOAT2
Chemokine signaling pathway	2.41×10−4	GNB2, CXCR4, RAC1, STAT1, FOXO3, CCL5, HCK, NFKBIA, NFKBIB, HRAS, IKBKG, SHC2, FGR, ARRB2, NCF1, ADCY2, CXCL16, AC092535.1, CCL2, GRK7, CCL24, CCL3, CCL13, CCL4, CCL21, CXCR1, ADCY8, CCL3L3, GNGT2, CCL3L1, CCL4L2, CXCL11, CCR7, CCR5, CCL26, CCL8