Table II.
A, A2780 xenografts | ||||||
---|---|---|---|---|---|---|
| ||||||
Treatment | n | Weight (g)
|
Tumor volume | Tumor weight | TIR | |
Day 0 | Day 31 | |||||
Control | 5/8 | 20.88±0.18 | 22.47±0.89 | 2465.0±459.1 | 2.12±0.34 | |
Dasatinib | 6/12 | 20.93±0.72 | 22.37±0.89 | 1400.2±231.3 | 1.67±0.30 | 43.197 |
Paclitaxel | 6/11 | 21.17±0.45 | 23.08±0.72 | 1016.9±176.3 | 1.34±0.20 | 58.764 |
Combined | 6/11 | 21.25±0.41 | 21.7±1.1 | 574.3±126.1 | 0.93±0.19 | 76.702 |
B, HO8910 xenografts | ||||||
---|---|---|---|---|---|---|
| ||||||
Treatment | n | Weight (g)
|
Tumor volume | Tumor weight | TIR | |
Day 0 | Day 31 | |||||
Control | 6/11 | 18.30±0.60 | 22.32±0.40 | 1695.2±162.5 | 2.65±0.28 | |
Dasatinib | 6/10 | 19.10±0.66 | 20.88±0.58 | 1119±168.6 | 1.55±0.30 | 33.99 |
Paclitaxel | 6/12 | 19.45±0.66 | 20.57±0.88 | 923.2±139.9 | 1.54±0.22 | 45.54 |
Combined | 6/10 | 17.28±0.51 | 20.35±0.57 | 698.3±145.7 | 1.65±0.42 | 58.51 |
Tumor volume (mm3); tumor weight (g); TIR (%). Data are presented as the mean ± standard deviation. TIR, tumor growth inhibitory rates.