Table 3.

Sex moderation of links between reward connectivity and self-reported nicotine dependence

NDSS scale	Model and variables	β	F	df for F	t	R2 (ΔR2)	95% CI for β
Tolerance	Step 1		5.20**	2,47		.18**
	Age	−.37			−2.68*		−.64, −.09
	Baseline CO	−.13			−.95		−.41, .15
	Step 2		2.59*	4,45		.19 (.01)
	Age	−.37			−2.58*		−.65, −.08
	Baseline CO	−.15			−1.04		−.44, .14
	Sex	.04			.28		−.24, .32
	Connectivity	.06			.45		−.22, .35
	Step 3		3.11*	5,44		.26 (.07)*
	Age	−.35			−2.58*		−.63, −.08
	Baseline CO	−.17			−1.24		−.46, .11
	Sex	.04			.29		−.23, .31
	Connectivity	.03			.21		−.25, .30
	Sex x Connectivity	.28			2.10*		.01, .55
Continuity	Step 1		.20	2,47		.01
	Step 2		.30	4,45		.03 (.02)
	Step 3		.36	5,44		.04 (.01)
Stereotypy	Step 1		2.54†	2,47		.10†
	Age	.21			1.42		−.09, .50
	Baseline CO	.18			1.27		−.11, .48
	Step 2		1.55	4,45		.12 (.02)
	Step 3		1.46	5,44		.14 (.02)

Note. NDSS: Nicotine Dependence Syndrome Scale; df: degrees of freedom; CI: confidence interval; CO: carbon monoxide. Step 1 included covariates (age and baseline CO). Step 2 included sex and network connectivity. Step 3 included the interaction of sex and network connectivity. Models, variables, and ΔR² significant at

^†p < .10;

^*p < .05;

^**p < .01.