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. Author manuscript; available in PMC: 2016 Feb 5.
Published in final edited form as: Mol Cell. 2015 Jan 15;57(3):422–432. doi: 10.1016/j.molcel.2014.12.016

Figure 5. Interaction of the POST state IRES with the L1 stalk and comparison of L1 positions in different ribosomal states.

Figure 5

(A) Depiction of three distinct L1 positions during translocation of the IRES, distance measurements were made between axes of mass-centers. From the unrotated PRE state (purple) to the rotated PRE state (yellow) (both from Fernández et al., 2014) L1 moves 14 Å towards the E-site. Upon translocation to the POST state (green) a movement of another 13 Å can be observed. (B) Comparison of the L1 stalk position in rotated 80S•CrPV IGR IRES complex (yellow) (Fernández et al., 2014) and 80S•CrPV-STOP (POST) complex (green) with corresponding canonical complexes (Budkevich et al., 2014).