Skip to main content
. Author manuscript; available in PMC: 2015 Aug 5.
Published in final edited form as: Cell Rep. 2015 Jul 16;12(4):610–621. doi: 10.1016/j.celrep.2015.06.057

Figure 1. Systemic deletion of Akt1 in p53−/− mice after tumor onset increased lifespan.

Figure 1

A. Schematic illustration showing crossing of mice to generate p53−/−Akt1f/f/R26CreERT2 mice. B. Immunoblot showing Akt1 deletion in several mouse tissues after injection of tamoxifen (Tam) to 6-week-old p53−/−Akt1f/f/R26CreERT2 mice. C. Kaplan-Meier plot showing life span of p53−/− or p53−/−Akt1f/f/R26CreERT2 mice after tamoxifen injection at 6 weeks of age (n=10).