Skip to main content
. Author manuscript; available in PMC: 2015 Aug 5.
Published in final edited form as: J Thorac Cardiovasc Surg. 2011 Sep 29;143(3):704–710. doi: 10.1016/j.jtcvs.2011.08.036

Figure 4.

Figure 4

CXCR3−/− mice do not develop aneurysms. (A) Gross photographs of aneurysm development in calcium chloride-treated right common carotid arteries vs. saline-treated left common carotid arteries in WT mice at day 0, day 28, and day 70 (right to left panels), bars represent artery diameter. (B) Bar graphs showing the average IEL perimeters, EEL perimeters, and vessel area of the calcium chloride-treated (black bars) and saline-treated (white bars) carotid arteries. WT, n=8; CXCR3−/−, n=8. Values are mean±SEM. *P<0.05. (C) Infiltrating CD45+ leukocytes in calcium chloride-treated vs. saline-treated carotid arteries in WT and CXCR3−/− mice were detected by immunohistochemistry and bar graphs represents the mean number of CD45+ cells per artery cross-section. WT, n=6; CXCR3−/−, n=5. Values are mean±SEM. *P<0.05.