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The functions of the HCV proteins
| Protein | Function |
|---|---|
| Core | Capsid |
| F (Frameshift) | Unknown |
| E1/E2 | Envelope glycoproteins |
| p7 | Viroporin (in vitro only) |
| NS2 | NS2/3 protease component |
| NS3 | Protease, helicase, NTPase |
| NS4A | NS3 protease co-factor |
| NS4B | Unknown-replicase component |
| NS5A | Unknown-?IFN sensitivity determinant |
| NS5B | RNA dependent RNA polymerase |
