Table 4.

Median values (95 % CI) of the texture and kinetic parameters

	Normal tissue	CR + PR	NR	p-valuea
Energy	58 [44; 74]	36 [33; 41]	45 [42; 55]	7.9 10−5
Entropy	157 [141; 172]	187 [181; 193]	175 [165; 180]	6.4 10−5
Contrast	8 [6; 10]	14 [11; 16]	13 [10; 16]	8.6 10−5
Homogeneity	165 [150; 176]	140 [134; 146]	149 [144; 156]	5.1 10−5
Correlation	22 [18; 29]	47 [42; 52]	47 [44; 50]	1.8 10−14
Inv. Diff. Moment	174 [161; 185]	148 [141; 153]	158 [153; 165]	4.2 10−5
Sum average	69 [65; 76]	119 [114; 124]	120 [109; 127]	3.6 10−19
Sum variance	70 [60; 76]	92 [88; 99]	97 [86; 110]	2.2 10−15
Difference variance	74 [67; 81]	87 [82; 93]	80 [78; 83]	4.6 10−3
SRE	0.009 [0.008; 0.009]	0.004 [0.0039; 0.0044]	0.0038 [0.0035; 0.0047]	6.2 10−19
LRE	126 [114; 144]	266 [246; 279]	284 [229; 309]	7.6 10−20
GLN	158 [137; 229]	432 [338; 589]	416 [298; 817]	1.2 10−10
RLN	71 [58; 86]	111 [74; 120]	105 [89; 205]	6.2 10−4
RP	0.68 [0.62; 0.72]	0.72 [0.71; 0.75]	0.70 [0.66; 0.73]	9.3 10−4
LGRE	0.75 [0.71; 0.78]	0.79 [0.78; 0.81]	0.77 [0.74; 0.80]	9.8 10−4
HGRE	3.11 [2.54; 3.99]	2.55 [2.33; 2.76]	2.83 [2.49; 3.34]	8.8 10−3
SRLGE	0.0060 [0.0056; 0.0067]	0.0033 [0.0031; 0.0034]	0.0030 [0.0028; 0.0036]	2.6 10−17
SRHGE	0.028 [0.024; 0.034]	0.011 [0.010; 0.012]	0.011 [0.009; 0.014]	6.4 10−18
LRLGE	93 [84; 101]	204 [189; 215]	214 [177; 251]	6.0 10−20
LRHGE	412 [343; 509]	679 [615; 745]	799 [592; 925]	1.9 10−9
Amplitude	_	75 [70; 80]	68 [59; 79]	_
Wash-out	_	0.04 [0.03; 0.06]	0.04 [0.008; 0.070]	_
Wash-in	_	0.72 [0.64; 0.83]	0.63 [0.42; 0.70]	_

Amplitude is given in arbitrary unit (AU), wash-in and wash-out in AU.s⁻¹

NR Non response, CR Complete response, PR Partial response

^aStatistical difference (Wilcoxon) between normal tissues and tumoral lesion