Table 4.
Group | SF%>28 | Age<13 years | MPI<0.40 | ||||||
---|---|---|---|---|---|---|---|---|---|
Measure | DMD, (n=26) | Controls (n=28) | P value | DMD, (n=17) | Controls (n=17) | P value | DMD, (n=22) | Controls (n=25) | P value |
Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | ||||
LV Shortening Fraction (%) | 34 (4) | 38 (4) | <.001 | 34 (4) | 38 (4) | .015 | 32 (5) | 38 (4) | <.001 |
Average LV Longitudinal Strain (%) | −14.3 (3.6) | −17.8 (3.0) | <.001 | −15.3 (3.6) | −17.6 (2.3) | .033 | −14.5 (3.4) | −17.4 (3.0) | .003 |
Average LV Circumferential Strain (%) | −20.2 (4.6) | −25.5 (3.5) | <.001 | −19.3 (3.9) | −25.9 (3.5) | <.001 | −20.7 (5.1) | −25.7 (3.2) | <.001 |
Average LV Longitudinal Strain Rate (1/s) | −1.2 (.4) | −1.3 (.3) | .16 | −1.2 (.3) | −1.3 (.2) | .07 | −1.1 (.3) | −1.3 (.3) | .045 |
Average LV Circumferential Strain Rate (1/s) | −1.9 (.5) | −2.4 (.5) | .001 | −1.9 (.5) | −2.3 (.5) | .013 | −1.9 (.5) | −2.4 (.5) | .004 |
Abbreviations: DMD – Duchenne muscular dystrophy, SF% - percent shortening fraction, TDI – tissue Doppler imaging, MPI – myocardial performance index, SD – standard deviation, LV - left ventricle, NS - not significant, SD - standard deviation