Table 3.
Multivariable Analysis examining the association between patients’ prognostic understanding and their QOL and mood during hospitalization for HCT
| Variables of Interest | Estimate of Difference (β) |
95% CI | P value |
|---|---|---|---|
| QOL (FACT-BMT) | |||
| Accurate vs. inaccurate prognostic understanding | −9.4 | [−16.8,−2.1] | P = 0.01 |
| QOL (FACT-TOI) | |||
| Accurate vs. inaccurate prognostic understanding | −7.2 | [−12.8, −1.6] | P = 0.01 |
| Fatigue (FACT-Fatigue) | |||
| Accurate vs. inaccurate prognostic understanding | −7.0 | [−11.6, −2.3] | P = 0.003 |
| Depression (HADS-Depression) | |||
| Accurate vs. inaccurate prognostic understanding | 1.7 | [0.26, 3.1] | P = 0.02 |
| Anxiety (HADS-Anxiety) | |||
| Accurate vs. inaccurate prognostic understanding | −0.2 | [−1.7, 1.3] | P = 0.81 |
| Depressive Syndrome (PHQ9) | |||
| Accurate vs. inaccurate prognostic understanding | 1.3 | [1.0–1.6] | P < 0.0001 |
The estimate of difference: estimated difference in scores compared to the reference group (inaccurate prognostic understanding) based on the results of the multivariable linear mixed models adjusting for age, comorbidities (HCT-CI), type of HCT, and time.