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. Author manuscript; available in PMC: 2016 Aug 4.
Published in final edited form as: Structure. 2015 Jul 16;23(8):1470–1481. doi: 10.1016/j.str.2015.06.009

Figure 8. Relationship between the binding site and resistance determinant of CBR703 and the RNAP active center: transcription inhibition by CBR703 does not require the RNAP trigger loop.

Figure 8

Effects of CBR703 on nucleotide addition by an E. coli RNAP derivative lacking the RNAP trigger loop (ΔTL RNAP; Temiakov et al., 2005).