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Addition of erlotinib to BPD-PDT improves therapeutic response of mice bearing NSCLC tumor xenografts. (A) Response of H460 tumors to erlotinib (n=6), BPD-PDT (n=19), or erlotinib/BPD-PDT (n=27). (B) Response of A549 tumors (n=7–11) to the same conditions. Three daily doses of erlotinib were administered prior to PDT. Tumor regrowth was monitored up to 90d post-PDT. For (B), a long-term survivor of PDT was euthanized (tumor-free) at 36 days due to unrelated illness.
