Representative traces of whole-cell Ba2+ currents activated by different voltages in IC neurons obtained from the control group (panel A), 3 h after ethanol intoxication (panel B) or 3 h (panel C), 24 h (panel D) or 48 h (panel E) during ethanol withdrawal. Of particular interest, the peak current density at −20 mV was enhanced 0.1-fold, 2.3-fold and 1.3-fold 3 h (−8 pA/pF), 24 h (−23 pA/pF) and 48 h (−16 pA/pF) during ethanol withdrawal, respectively, compared with the control group (−7 pA/pF). The peak current density at −20 mV was not altered 3 h after ethanol intoxication (−8 pA/pF) compared with the control group (−7 pA/pF). Whole-cell Ba2+ currents were activated as shown in the inset (panel E).