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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: DNA Repair (Amst). 2015 Jun 16;33:43–59. doi: 10.1016/j.dnarep.2015.06.003

Figure 7. Schematic of fluorometric dye displacement kinetic assay.

Figure 7

This assay utilizes a small molecule with unique fluorescence properties dependent on binding to duplex DNA to analyze partial unwinding of a duplex DNA substrate by a helicase when it encounters a lesion that blocks its progression. See text for details.