Table 1.
Baseline clinical charactersitics in the study population overall and by quartile of LV LS. LS is shown as absolute value.
Numbers represent mean ± S.D. for continuous variables and N (%) for categorical variables.
| Overall (n=447) | Quartile 1: <13.2 (n=111) | Quartile 2: 13.2 to 15.6 (n=112) | Quartile 3: 15.6 to 18.3 (n=112) | Quartile 4: >18.3 (n=112) | P for trend | |
|---|---|---|---|---|---|---|
| Age (years) | 70.3 ± 9.8 | 70.2 ± 9.5 | 69.8 ± 10.4 | 69.9 ± 9.1 | 71.2 ± 10.2 | 0.47 |
| Female | 240 (53.7%) | 49 (44.1%) | 58 (51.8%) | 65 (58.0%) | 68 (60.7%) | 0.008 |
| White | 359 (80.3%) | 88 (79.3%) | 93 (83.0%) | 92 (82.1%) | 86 (76.8%) | 0.62 |
| Enrollment in Russia/Georgia | 107 (23.9%) | 26 (23.4%) | 23 (20.5%) | 28 (25.0%) | 30 (26.8%) | 0.42 |
| Enrollment Strata: Prior Hospitalization | 289 (64.7%) | 68 (61.3%) | 78 (69.6%) | 74 (66.1%) | 69 (61.6%) | 0.90 |
| Co-morbidities | ||||||
| Hypertension | 411 (92.2%) | 104 (93.7%) | 104 (92.9%) | 101 (90.2%) | 102 (91.9%) | 0.48 |
| Myocardial Infarction | 115 (25.8%) | 44 (39.6%) | 25 (22.3%) | 24 (21.4%) | 22 (19.8%) | 0.001 |
| Coronary Revascularization | 130 (29.1%) | 39 (35.1%) | 47 (42.0%) | 24 (21.4%) | 20 (18.0%) | <0.001 |
| Stroke | 47 (10.5%) | 17 (15.3%) | 9 (8.0%) | 13 (11.6%) | 8 (7.2%) | 0.11 |
| Atrial Fibrillation | 193 (43.3%) | 65 (58.6%) | 54 (48.2%) | 41 (36.6%) | 33 (29.7%) | 0.0001 |
| Diabetes | 171 (38.3%) | 45 (40.5%) | 58 (51.8%) | 36 (32.1%) | 32 (28.8%) | 0.008 |
| Obesity | 262 (58.7%) | 60 (54.1%) | 75 (67.0%) | 61 (54.5%) | 66 (59.5%) | 0.86 |
| NYHA Functional Class | 0.16 | |||||
| 1 | 33 (7.4%) | 7 (6.3%) | 11 (9.8%) | 5 (4.5%) | 10 (9.1%) | |
| 2 | 241 (54.2%) | 68 (61.3%) | 58 (51.8%) | 63 (56.2%) | 52 (47.3%) | |
| 3 | 168 (37.8%) | 36 (32.4%) | 41 (36.6%) | 44 (39.3%) | 47 (42.7%) | |
| 4 | 3 (0.7%) | 0 (0.0%) | 2 (1.8%) | 0 (0.0%) | 1 (0.9%) | |
| Physical Characteristics | ||||||
| BMI (kg/m2) | 32.5 ± 6.9 | 31.5 ± 6.6 | 33.7 ± 6.9 | 31.7 ± 6.7 | 32. 9 ± 7.2 | 0.45 |
| Heart rate (bpm) | 68 ± 11 | 72 ± 12 | 68 ± 12 | 68 ± 13 | 64 ± 8 | <0.001 |
| Systolic blood pressure (mmHg) | 126 ± 15 | 125 ± 16 | 127 ± 16 | 128 ± 15 | 126 ± 14 | 0.44 |
| Diastolic blood pressure (mmHg) | 72 ± 11 | 73 ± 11 | 74 ± 11 | 71 ± 12 | 72 ± 10 | 0.09 |
| Laboratory Values | ||||||
| eGFR (mL/min per 1.73 m2) | 66 ± 22 | 65 ± 23 | 67 ± 22 | 66 ± 21 | 66 ± 20 | 0.84 |
| Creatinine (mg/dL) | 1.14 ± 0.34 | 1.19 ± 0.34 | 1.12 ± 0.35 | 1.12 ± 0.34 | 1.12 ± 0.35 | 0.15 |
| Hematocrit (%) | 38.9 ± 4.7 | 39.5 ± 4.5 | 39.2 ± 4.5 | 38.7 ± 4. 8 | 38.2 ± 4.9 | 0.03 |