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. 2015 Aug 5;10(8):e0134558. doi: 10.1371/journal.pone.0134558

Fig 4. Immunohistochemical analysis for PCNA (proliferating cell nuclear antigen), Ki-67 and BrdU of the gastric mucosa of the rats subjected to induction of chronic ulcer by 30% acetic acid.

Fig 4

Animals were treated orally with 1% Tween-80 aqueous solution (control group), pantoprazole (40 mg/kg) or CIN (100 mg/kg) for 14 days. The filled arrow indicates the absence of the epithelial layer (ulcer area internal) and the dashed arrow indicates epithelial layer remaining (ulcer edge). Microphotographs depict the immunoreactivity for PCNA, Ki-67 and BrdU in the groups, magnification 200x (control) and 500x (CIN or pantoprazole).