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A) Substrate affinity of FAHA, DFAHA, and TFAHA to different recombinant HDACs in vitro. The substrate affinity is expressed as Kcat. B) Maximum catalytic rate of FAHA, DFAHA, and TFAHA for different recombinant HDACs in vitro, expressed as v max. C) The concentration required for half of the maximal catalytic activity for all recombinant HDACs expressed as k m.
