Table 4. Adverse events during therapeutic plasma exchange (n = 466 single sessions).

Adverse event	No.	Treatment
Local infection due to vascular access	1	Local antiseptics
Local bleeding due to vascular access	3	Local compression
Pain due to vascular access	1	Peripheral analgetics
Electrolyte imbalance (hypocalcaemia)	1	10% calcium gluconate
Temporary paresthesia	1	No treatment
Allergic reaction	3	Antihistamines + Prednisolone
Moderate hypotension	2	Crystalloid infusion
Coagulation imbalance	4	Specific substitution
Dislocation of peripheral vascular access	1	Change of access
Failed puncture for central venous access	1	No treatment
Vasovagal syncope	1	Symptomatic treatment
Systemic infection without sepsis	4	Antibiotics
Systemic infection with sepsis	1	Sepsis treatment on ICU
Thrombosis and pulmonary embolism	1	Anticoagulation
Total adverse events	25

ICU = intensive care unit, Moderate hypotension = systolic blood pressure below 95 mmHg, No. = number.