Table 4. Most differentially regulated transcripts in thymus as identified by IPA microarray analysis.
| Symbol | Entrez Gene Name | Fold Change | IPA Networks a | Location | Type(s) |
|---|---|---|---|---|---|
| MALT1 | Mucosa associated lymphoid tissue lymphoma translocation gene 1 | 7.359 | 1 | Cytoplasm | Peptidase |
| IGJ | Immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | 4.845 | 1 | Extracellular Space | Other |
| UNG | Uracil-DNA glycosylase | 3.820 | 2 | Nucleus | Enzyme |
| CWC15 | CWC15 spliceosome-associated protein homolog (S. cerevisiae) | 2.829 | 4 | Nucleus | Other |
| FN1 | Fibronectin 1 | 2.635 | 1 | Extracellular Space | Enzyme |
| COPE | Coatomer protein complex, subunit epsilon | 2.601 | 2 | Cytoplasm | Transporter |
| NBL1 | Neuroblastoma, suppression of tumorigenicity 1 | 2.384 | 2 | Nucleus | Other |
| NFE2L2 | Nuclear factor (erythroid-derived 2)-like 2 | 2.133 | 1 | Nucleus | Transcription regulator |
| BAK1 | BCL2-antagonist/killer 1 | 1.726 | 1 | Cytoplasm | Other |
| COX6A1 | cytochrome c oxidase subunit VIa polypeptide 1 | -1.643 | 2 | Cytoplasm | Enzyme |
| DDT | D-dopachrome tautomerase | -1.950 | 1 | Cytoplasm | Enzyme |
| C12H9orf89 | Chromosome 12 open reading frame, human C9orf89 | -1.998 | 3 | Cytoplasm | Other |
| GRAP2 | GRB2-related adaptor protein 2 | -2.059 | 1 | Cytoplasm | Other |
| ACOX1 | Acyl-CoA oxidase 1, palmitoyl | -2.110 | 1 | Cytoplasm | Enzyme |
| PTP4A3 | Protein tyrosine phosphatase type IVA, member 3 | -2.413 | 1 | Plasma Membrane | Phosphatase |
| CD2 | CD2 molecule | -2.584 | 1 | Plasma Membrane | Transmembrane receptor |
| CD8A | CD8a molecule | -2.791 | 1 | Plasma Membrane | Other |
| SATB1 | SATB homeobox 1 | -3.233 | 1 | Nucleus | Transcription regulator |
| SLA | Src-like-adaptor | -3.521 | 1 | Plasma Membrane | Other |
a Networks identified by Ingenuity pathway Analysis are included in S1 File.