Table 6. KEGG pathway enrichment analysis for genes upregulated in the culture with KCM+ vs KCM- (significant pathways for the downregulated ones were not observed).
LM | DM | |||
---|---|---|---|---|
Pathway | Adj-p | Pathway | Adj-p | |
6h | Ubiquitin mediated proteolysis | 1.00E-03 | - | |
mTOR signaling pathway | 4.34E-02 | |||
12h | Neurotrophin signaling pathway | 8.03E-05 | - | |
Phosphatidylinositol signaling system | 5.50E-03 | |||
Endocytosis | 2.28E-02 | |||
24h | RNA transport | 1.50E-03 | Focal adhesion | 4.85E-05 |
Insulin signaling pathway | 4.70E-03 | |||
Ubiquitin mediated proteolysis | 4.90E-03 | |||
Homologous recombination | 7.60E-03 | |||
mRNA surveillance pathway | 8.30E-03 | |||
SNARE interactions in vesicular transport | 9.50E-03 | |||
Spliceosome | 1.24E-02 | |||
Cell cycle | 1.66E-02 | |||
Pyrimidine metabolism | 1.89E-02 | |||
Ribosome biogenesis in eukaryotes | 2.23E-02 | |||
Wnt signaling pathway | 4.46E-02 |