Table 5. Significantly upregulated metabolites amongst the five cells lines in the negative1 and positive2 acquisition modes.
| Compound LC MS/MS ID | HMDID | Common Name | Exact Neutral Monoisotopic Mass | Maximum Fold increase | Highest Mean Cell Line | Lowest Mean Cell Line | P value |
|---|---|---|---|---|---|---|---|
| 3.43_347.0453m/z2 | HMDB00195 | Inosine | 268.0808 | 8.12 | MDAPCa2b | LNCAP | 2.50E-3 |
| 4.19_307.0838n1 | HMDB00125 | Glutathione | 307.0838 | 627 | RC77N-E | MDAPCa2b | 4.18E-2 |
| 5.22_346.0552m/z1 | HMDB03540 | 3'-AMP | 347.0631 | 14 | RC77N-E | RC77T-E | 1.08E-8 |
| 5.33_323.0287m/z1 | HMDB11641 | Uridine 2'- phosphate | 324.0359 | 20.8 | MDAPCa2b | RC77T-E | 3.45E-8 |
| 5.57_362.0504m/z1 | HMDB01397 | Guanosine monophosphate | 363.058 | 27.6 | MDAPCa2b | RC77T-E | 3.24E-9 |
| 6.50_606.0743m/z1 | HMDB00304 | acetylgalactosamine | 607.0816 | 30.3 | MDAPCa2b | RC77T-E | 3.91E-9 |
| 2.29_276.185m/z2 | HMDB13131 | Hydroxyhexanoycarnitine | 276.185 | 275 | MDAPCa2b | LNCAP | 1.60e-7 |
| 2.74_161.10552 | HMDB00062 | L-Carnitine | 161.1055 | 3.2 | MDAPCa2b | LNCAP | 1.10e-3 |
| 5.30_612.1524m/z2 | HMDB03337 | Oxidized glutathione | 612.1524 | 1.97 | MDAPCa2b | LNCAP | 1.55E-5 |