Fig. 6.
Daytime dialysis of a triple cocktail of antagonists (5 mM ATR, 500 μM SPA, and 0.5 mM MDL, n = 6) in the VRC had no significant effect (P ≥ 0.509) on any respiratory parameter relative to time-control studies (n = 7). A: minute ventilation (VI, liters/min); B: frequency (F, breaths/min); C: tidal volume (VT, liters/breath). The first data point represents the last 15-min bin of hour 1. Closed symbols and bar indicate period of cocktail dialysis; open symbols indicate mCSF dialysis. F and P indicate values for interaction term from two-way RM ANOVA.