Skip to main content
. 2015 Aug;4(4):243–267. doi: 10.3978/j.issn.2304-3881.2015.05.05

Figure 1.

Figure 1

A schematic diagram representing retinoid-xenobiotic interaction. Retinoids (all-trans-retinoic acid and 9-cis-retinoic acid) are ligands for canonical retinoic acid receptors (RARs) and retinoid X receptors (RXRs). RXRs are common heterodimerization partners for xenobiotic receptors (CAR and SXR). The activation of xenobiotic-responsive pathways, like the CAR/RXR or SXR/RXR pathways, alters the balance and consequently the functioning of canonical retinoid-responsive pathways (RAR/RXR pathways).