Table 2. Characteristics of t-MN patients carriers of FANC variants.

UPN	Primary tumor, age	t-MN latency, karyotype	Gene symbol and AA change	NCBI rs and/or COSMIC numbers	Control tissue
6531	Breast, 57 years	72 months, del5q31	FANCA L6F	rs189841793	Breast cancer and normal breast tissue
3155	NHL, 69 years	66 months, complex	FANCA S90T	Novel	NHL biopsy
5993	HL, thyroid, 52 years	48 months, Del7	FANCD2 T1376A	Novel	HL biopsy and normal lymphnode
6190	HL, 47 years	208 months, Trisomy 8	FANCD2 P256S	Novel	Buccal swab and hair follicle
6828	HL, 60 years	112 months, n.a.	FANCD2 M1023V;	Novel	HL biopsy
2885	Breast/ adrenal, na	na	FANCJ I364V FANCC L36F	Novel	Not available

Abbreviations: HL, Hodgkin lymphoma; NHL, Non-Hodgkin lymphoma; t-MN, therapy-related myeloid neoplasms. NCBI and Cosmic database variant number and the reported frequency is indicated.