Table 3. Association of TP53 mutation with other gene mutations.

Variables	No. of patients with alteration (%)			P-value
	Whole cohort (n=500)	TP53-mutated patients (n=35)	TP53 wild-type patients (n=465)
FLT3/ITD	113 (22.6)	0 (0)	113 (24.3)	0.0002
FLT3/TKD	38 (7.6)	0 (0)	38 (8.2)	0.097
NRAS	61 (12.2)	2 (5.7)	59 (12.7)	0.2918
KRAS	16 (3.2)	0 (0)	16 ((3.4)	0.6175
PTPN11	18 (3.6)	2 (5.7)	16 (3.4)	0.3635
KIT	15 (3.0)	0 (0)	15 (3.2)	0.6143
JAK2	3 (0.6)	0 (0)	3 (0.6)	>0.9999
WTI	33 (6.6)	1 (2.9)	32 (6.9)	0.7195
NPM1	103 (20.6)	1 (2.9)	102 (21.9)	0.0041
CEBPA	66 (13.2)	2 (5.7)	64 (13.8)	0.2957
RUNX1	62 (12.4)	2 (5.7)	60 (12.9)	0.2912
MLL/PTD	27 (5.4)	0 (0)	27 (5.8)	0.2444
ASXL1	50 (10.0)	2 (5.7)	48 (10.3)	0.5613
IDH1	27 (5.4)	1 (2.9)	26 (5.6)	0.7115
IDH2	55 (11)	1 (2.9)	54 (11.6)	0.1584
TET2	66 (13.2)	2 (5.7)	64 (13.8)	0.2957
DNMT3A	70 (14.0)	1 (2.9)	69 (14.8)	0.045