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WOX5 signal and CLE40 peptide locations and their effect on CSC fate. WOX5 is expressed in the QC and signals to maintain CSCs distal to the QC. CLE40 is expressed in CCs, the differentiating daughters of the CSCs, and secreted into the apoplast, where it can act through plasma membrane-localized receptor-like kinases and inhibit the WOX5 signal. CCs are identifiable by their stainable starch granules.
