Table 1.
MS and selection of 1H and 13C-NMR data of compounds X, Y, Z and filipin III
| Compound | MS | 1H and 13C-NMR position | |
|---|---|---|---|
| 26 | 1′ | ||
| X (1′-hydroxyfilipin I) | [M+Na]+
661.6 |
δH: 2.24 and 2.29 δC: 37.94 |
δH: 3.72 δC: 70.47 |
| Y (filipin I) | [M+Na]+
645.5 |
δH: 2.25 and 2.35 δC: 37.89 |
δH: 1.44 and 1.68 δC : 29.47 |
| Z (filipin II) | [M+Na]+
661.5 |
δH: 3.93 δC: 72.11 |
δH: 1.43 and 1.68 δC: 29.60 |
| Filipin III | [M+H]+
655.4 |
δH: 3.94 δC: 73.00 |
δH: 3.66 δC: 69.50 |
Only the chemical shifts of the most relevant signals are listed. Positions are labelled according to their number in the polyketide backbone (Fig. 6).