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. Author manuscript; available in PMC: 2015 Aug 6.
Published in final edited form as: J Am Soc Nephrol. 2010 Jul 1;21(10):1620–1627. doi: 10.1681/ASN.2010010046

Figure 2.

Figure 2

Sirtuins protect kidney health. Shown is an overview of sirtuin-regulated processes with positive effect on kidney health. Nutritional cues and different forms of stress activate sirtuins in different tissues and cell types. This results in multiple local and systemic effects, which are likely to retard renal aging and result in renoprotection.