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. 2015 Aug 7;22(1):65. doi: 10.1186/s12929-015-0171-x

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© Huang et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Adjuvant effect of rlipoA-RBD. To demonstrate adjuvant effect of rlipoA-RBD, the enhancement of anti-OVA IgG response was evaluated by co-administration of rlipoA-RBD and OVA. BALB/c mice were immunized with 3 × 2 μg of OVA formulated either with or without various amounts of rlipoA-RBD (0.3 and 3 μg), 10 μg of A-rRBD, or alum as positive control. Serum titer was determined by RBD-specific ELISA